At TrialSphere Clinical Research (formerly MD First Research Chandler) in Chandler, Arizona, we welcome individuals and families who want to explore clinical research options for neurological and other health conditions. We partner with people across Arizona to advance care through carefully designed clinical studies led by an experienced team, with a primary focus on Dementia, Migraine, and Neuropathy, and expanding into additional areas as new opportunities open. We follow strict ethical and regulatory standards so that every participant’s rights, safety, and privacy are respected. Your questions matter here, and we are committed to making research clear, supportive, and accessible, so you can decide with confidence whether participation is right for you.
Participation Essentials
A Research Center Built Around People
Mission
What We Offer Participants
What we offer:
- Pioneering clinical studies in the heart of Arizona
- Expertise in neurological wellness among other areas of care
- A broad spectrum of enrolling and forthcoming clinical studies
- Opportunities to access innovative therapies before they are widely available
Every study is different, and eligibility varies. We will explain options clearly and recommend a study only when it fits health needs and goals.
Why People Participate
People participate in clinical research for many reasons, including hope for better options, interest in new approaches, and the desire to help future patients.
Participants often value:
- Around the clock access to our dedicated healthcare team for support during the study
- Opportunities for enhanced health monitoring and follow up
- The chance to contribute to medical advancements that may improve future care
A clinical study may or may not help a condition directly. Participation helps build knowledge that can improve care for others.
What to Expect If You Join
We guide you step by step, with clear information and no pressure.
- 1. Start with a conversation: Complete the interest form or contact our team directly
- 2. Eligibility review: A coordinator reviews your health history and the study requirements
- 3. Screening visit: If appropriate, an in clinic visit is scheduled to confirm eligibility
- 4. Informed consent: We explain the study purpose, procedures, risks, benefits, and alternatives before you decide
- 5. Study visits and ongoing support: A clear visit schedule is provided, with a team available for questions
- 6. Follow up and next steps: When the study ends, outcomes are reviewed and next steps are discussed
Participation remains voluntary throughout the study.
Your Safety, Privacy, and Rights
You can expect:
- Privacy and confidentiality strictly safeguarded
- Clear answers to questions before and during participation
- Freedom to withdraw at any time without penalty or loss of care
We are committed to keeping the research experience clear, supportive, and accessible.
Reimbursement and Travel Support
Current Studies
SonusMed Hypertension Study (High Blood Pressure)
- Adults aged 21-75 with hypertension (≥130/80 mmHg)
- Diagnosed with high blood pressure on at least three separate occasions
- NOT taking more than one antihypertensive medication
- NOT using weight loss medications (e.g., Ozempic, Mounjaro)
Observation Study for Alzheimer's Disease
- Adults aged 60 and older who have undergone testing or screening and have been diagnosed with mild cognitive impairment or mild dementia due to Alzheimer’s disease
- Individuals who are considering or are being evaluated for newer treatments for mild cognitive impairment or mild Alzheimer’s disease
- Individuals who have a reliable care partner willing to provide written informed consent for participation
Early Cognitive Decline Study
- Adults aged 55 to 85 years of age
- Have gradual cognitive decline that is noticeable by self or someone close
- Have 1 clinical feature of dementia with Lewy-bodies, such as (but not limited to) stiffness, tremor, and/or acting out dreams
- Have markers of amyloid-beta and alpha-synuclein found in blood and CSF that meet the study inclusion
- Have a reliable study partner
Chronic Migraine Study
- Adults aged 18+
- Diagnosis of chronic migraine
- First migraines started under an age of 50
Episodic Migraine Study
- Adults aged 18+
- Diagnosis of episodic migraine
- First migraines started under an age of 50
Stories And Updates
WHAT May be Featured
- New clinical studies and enrollment opportunities
- Research updates and milestones
- Educational resources and wellness insights
- Community events and announcements
Get Involved
There are several ways to get involved with TrialSphere Clinical Research. Upcoming educational and community events are listed on the Home page and offer a welcoming way to learn more about current and future studies. Questions about participation can be submitted through the Contact Us page. For study specific questions, the Ask An Expert MailChimp form is available. Social media channels provide an easy way to stay connected with updates, announcements, and new research opportunities, and the Newsletter sign up option offers periodic study updates delivered directly to inboxes.
For detailed information about how clinical studies work, visit the Research Studies Page.