Welcome To TrialSphere
At TrialSphere Clinical Research (formerly MD First Research Chandler) in Chandler, Arizona, we welcome individuals and families who are interested in learning about clinical research opportunities related to neurological and other health conditions. Our experienced team conducts carefully designed studies with a primary focus on Dementia, Migraine, and Neuropathy.
We are committed to maintaining high ethical and regulatory standards so that every participant’s rights, safety, and privacy are respected.
Our team works to make the research experience clear, supportive, and accessible, and we strive to ensure that individuals and families feel comfortable asking questions and exploring whether participation is right for them.
Whether you are considering taking part in a study, referring a patient, or exploring a potential collaboration as a sponsor, TrialSphere Clinical Research is dedicated to supporting responsible research and contributing to scientific understanding within our community.
Participants
Eligible participants may receive new treatments, compensation for time and travel, and may withdraw at any time.
Providers
Eligible patients may receive free access to comprehensive diagnostic testing, intensive monitoring, and cutting-edge treatments.
Sponsors/CROs
Drive rapid enrollment with our site’s 2-week start-up, central IRB efficiency, and strong commitment to diversity.
51+
Studies Conducted
Since 2022
Since 2022
791+
Study Participants
Since 2022
Since 2022
12
Study Drugs
Approved
Approved
Participate in a Study
Join our clinical studies and help pave the way for groundbreaking treatments.
Memory & Cognitive Health
Major Depressive Disorder
Type 2 Diabetes
Idiopathic Rem Behavior Disorder
Migraines
Painful Diabetic Neuropathy
Memory & Cognitive Health
Migraine
Neurology
Neuropathy
Mental Health
Metabolic Health
Sleep Health
Cardiovascular Health
Musculoskeletal Pain
Other / Future Studies
Events
Testimonials
"My wife is in an Alzheimer’s treatment program with monthly infusions and MRIs. MD First has made the process very comfortable, and the staff is always kind and informative. We’re in our fourth month and remain hopeful about the results."
J. Townsend | Patient Study Partner
September 8, 2025
“Very cooperative and caring. Full attention is given to the patient and attendant to resolve any doubts etc.”
N. Varma | Patient
September 8, 2025
"Great experience."
T. Baker | Patient
September 8, 2025
“I was so impressed with the staff when visiting your office last week! You are certainly surrounded by some fine people.”
K.W. | Patient | March 2025
“This Botox study not ONLY helped my migraines and headaches, it taught me a lot about myself and I really enjoyed the staff. They are so friendly, caring, kind and fun!.”
D.W. | Patient
“The staff is amazing! They are very friendly, communicative, caring and professional. I highly recommend them.”
A.M. | Patient
“Very professional, caring, always upbeat. Glad to participate in the research program.”
W.L. | Patient
“Everything that my Wife {Diane} has had done the MD First Research. Has Been Great. Everyone that works there is so Caring. Thanks!!!”
L.S. | Caregiver
“Very friendly and professional!”
S.C. | Caregiver
“Everyone was really nice, professional, approachable, easy to reach, and accommodating to personal schedules.”
Anonymous | Caregiver
“If I could give a higher score than “Very Satisfied”, then I would! All the staff is wonderful!”
Anonymous | Patient
“I don't know how it could be better.”
Anonymous | Patient